As to how you do it read the EVGA manual as it is all described:
EVGA | EVGA X58 SLI Motherboard | EVGA X58 SLI Motherboard
As to the 24/7 you will just note a spike in your electric bill running a 1,000 watt PSU 24/7 even though it only draws what it needs it is similar to running a room air conditioner as to your power consumption.
Those graphics cards run idle @ 60>65C. Under liquid I can get them down to @40>45C.
Under use they do not go up much. Certainly should not go over 70C.
As mentioned I run an older quad socket 775 rated 2.66 at 3.4 very stable under liquid. It idles @40C and under 100% CPU runs close to 70C. I could not do this with the stock fan. I have run it at 3.8 just to get a benchmark but it was not stable for long.
So read the manual. You can either adjust the FSB or adjust the CPU multiplier and in either case you will need to manually up the CPU voltage and that is where the heat comes from.
As to the RAM I would not OC it. It is much more sensitive than the CPU and with all due respect EVGA boards have a history of frying RAM.
Also note you are voiding any and all warranties by overclocking.
Let us know if we can help further.
By the way SpeedFan is a good monitor for your temps:
SpeedFan - Access temperature sensor in your computer
If you want to stress test try Prime95 Torture Test:
Prime95 (32bit) - 25.8 Download - EXTREME Overclocking
Whether or not overclocking improves performance is questionable on many sub levels.
It is up to you if it is worth the risk of burning out hardware.
I did the RAM thing on my first EVGA board and burned out 2 sets of 4GB before I learned not to OC the RAM on that board at least. Anyway just beware of the risks. No nets here.