Bros comp slow

Hi all, now my brother has bought a computer but when i come home to visit it runs incredibly slow, its todays spec 3.2Ghz 1gig ram etc...
I've run all the usual programs virus scans etc but nothing so if someone could have a look at his hijackthis file please:

Logfile of HijackThis v1.99.1
Scan saved at 10:32:45, on 22/08/2005
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\csrss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Ahead\InCD\InCDsrv.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
c:\PROGRA~1\mcafee.com\vso\mcvsrte.exe
C:\PROGRA~1\McAfee.com\PERSON~1\MPFSERVICE.exe
C:\PROGRA~1\McAfee\SPAMKI~1\MSKSrvr.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\System32\hkcmd.exe
C:\Program Files\Java\jre1.5.0_04\bin\jusched.exe
C:\PROGRA~1\mcafee.com\agent\mcagent.exe
C:\WINDOWS\system32\gsicon.exe
C:\Program Files\NASDAK\OmniMouse Driver\4.06\MOUSE32A.EXE
C:\WINDOWS\SOUNDMAN.EXE
C:\Program Files\Ahead\InCD\InCD.exe
C:\Program Files\CyberLink\PowerDVD\PDVDServ.exe
C:\Program Files\Winamp\winampa.exe
C:\PROGRA~1\mcafee.com\vso\mcvsshld.exe
C:\PROGRA~1\mcafee.com\mps\mscifapp.exe
C:\PROGRA~1\McAfee\SPAMKI~1\MSKAgent.exe
c:\progra~1\mcafee.com\vso\mcvsescn.exe
C:\PROGRA~1\McAfee.com\PERSON~1\MpfTray.exe
C:\Program Files\D-Tools\daemon.exe
C:\Program Files\Common Files\Real\Update_OB\realsched.exe
C:\WINDOWS\vsnpt513.exe
C:\WINDOWS\system32\dslagent.exe
C:\Program Files\PeerGuardian2\pg2.exe
C:\WINDOWS\system32\wdfmgr.exe
C:\PROGRA~1\McAfee.com\PERSON~1\Mp***ent.exe
c:\PROGRA~1\mcafee.com\vso\mcshield.exe
C:\WINDOWS\System32\alg.exe
C:\WINDOWS\System32\svchost.exe
C:\PROGRA~1\MOZILL~1\FIREFOX.EXE
C:\Program Files\Hijack Thius\HijackThis.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.hotmail.com/
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = about:blank
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 5.0\Reader\ActiveX\AcroIEHelper.ocx
O2 - BHO: McBrwHelper Class - {227B8AA8-DAF2-4892-BD1D-73F568BCB24E} - c:\PROGRA~1\mcafee.com\mps\mcbrhlpr.dll
O2 - BHO: McAfee PopupKiller - {3EC8255F-E043-4cae-8B3B-B191550C2A22} - c:\program files\mcafee.com\mps\popupkiller.dll
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O2 - BHO: PCTools Site Guard - {5C8B2A36-3DB1-42A4-A3CB-D426709BBFEB} - C:\PROGRA~1\SPYWAR~1\tools\iesdsg.dll
O2 - BHO: (no name) - {AA58ED58-01DD-4d91-8333-CF10577473F7} - (no file)
O2 - BHO: PCTools Browser Monitor - {B56A7D7D-6927-48C8-A975-17DF180C71AC} - C:\PROGRA~1\SPYWAR~1\tools\iesdpb.dll
O2 - BHO: FlashFXP Helper for Internet Explorer - {E5A1691B-D188-4419-AD02-90002030B8EE} - C:\PROGRA~1\FlashFXP\IEFlash.dll
O3 - Toolbar: McAfee VirusScan - {BA52B914-B692-46c4-B683-905236F6F655} - c:\progra~1\mcafee.com\vso\mcvsshl.dll
O3 - Toolbar: (no name) - {2318C2B1-4965-11d4-9B18-009027A5CD4F} - (no file)
O4 - HKLM\..\Run: [IgfxTray] C:\WINDOWS\System32\igfxtray.exe
O4 - HKLM\..\Run: [HotKeysCmds] C:\WINDOWS\System32\hkcmd.exe
O4 - HKLM\..\Run: [SunJavaUpdateSched] C:\Program Files\Java\jre1.5.0_04\bin\jusched.exe
O4 - HKLM\..\Run: [MCAgentExe] c:\PROGRA~1\mcafee.com\agent\mcagent.exe
O4 - HKLM\..\Run: [MCUpdateExe] C:\PROGRA~1\mcafee.com\agent\McUpdate.exe
O4 - HKLM\..\Run: [NeroFilterCheck] C:\WINDOWS\system32\NeroCheck.exe
O4 - HKLM\..\Run: [GSICONEXE] gsicon.exe
O4 - HKLM\..\Run: [LWBMOUSE] C:\Program Files\NASDAK\OmniMouse Driver\4.06\MOUSE32A.EXE
O4 - HKLM\..\Run: [SoundMan] SOUNDMAN.EXE
O4 - HKLM\..\Run: [InCD] C:\Program Files\Ahead\InCD\InCD.exe
O4 - HKLM\..\Run: [RemoteControl] "C:\Program Files\CyberLink\PowerDVD\PDVDServ.exe"
O4 - HKLM\..\Run: [WinampAgent] C:\Program Files\Winamp\winampa.exe
O4 - HKLM\..\Run: [VSOCheckTask] "c:\PROGRA~1\mcafee.com\vso\mcmnhdlr.exe" /checktask
O4 - HKLM\..\Run: [VirusScan Online] "c:\PROGRA~1\mcafee.com\vso\mcvsshld.exe"
O4 - HKLM\..\Run: [MPSExe] c:\PROGRA~1\mcafee.com\mps\mscifapp.exe /embedding
O4 - HKLM\..\Run: [MSKAGENTEXE] C:\PROGRA~1\McAfee\SPAMKI~1\MSKAgent.exe
O4 - HKLM\..\Run: [MSKDetectorExe] C:\PROGRA~1\McAfee\SPAMKI~1\MskDetct.exe /startup
O4 - HKLM\..\Run: [MPFExe] C:\PROGRA~1\McAfee.com\PERSON~1\MpfTray.exe
O4 - HKLM\..\Run: [DAEMON Tools-1033] "C:\Program Files\D-Tools\daemon.exe" -lang 1033
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Common Files\Real\Update_OB\realsched.exe" -osboot
O4 - HKLM\..\Run: [SNPT513] C:\WINDOWS\vsnpt513.exe
O4 - HKLM\..\Run: [DSLAGENTEXE] dslagent.exe USB
O4 - HKCU\..\Run: [MSKAGENTEXE] C:\PROGRA~1\McAfee\SPAMKI~1\MskAgent.exe
O4 - HKCU\..\Run: [ccleaner] "C:\Program Files\CCleaner\ccleaner.exe" /AUTO
O4 - HKCU\..\Run: [PeerGuardian] C:\Program Files\PeerGuardian2\pg2.exe
O8 - Extra context menu item: &Google Search - res://C:\Program Files\Google\GoogleToolbar1.dll/cmsearch.html
O8 - Extra context menu item: Backward &Links - res://C:\Program Files\Google\GoogleToolbar1.dll/cmbacklinks.html
O8 - Extra context menu item: Cac&hed Snapshot of Page - res://C:\Program Files\Google\GoogleToolbar1.dll/cmcache.html
O8 - Extra context menu item: Si&milar Pages - res://C:\Program Files\Google\GoogleToolbar1.dll/cmsimilar.html
O8 - Extra context menu item: Translate into English - res://C:\Program Files\Google\GoogleToolbar1.dll/cmtrans.html
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.5.0_04\bin\npjpi150_04.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.5.0_04\bin\npjpi150_04.dll
O9 - Extra button: Spyware Doctor - {2D663D1A-8670-49D9-A1A5-4C56B4E14E84} - C:\PROGRA~1\SPYWAR~1\tools\iesdpb.dll
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O16 - DPF: {17492023-C23A-453E-A040-C7C580BBF700} (Windows Genuine Advantage Validation Tool) - http://go.microsoft.com/fwlink/?linkid=39204
O16 - DPF: {4ED9DDF0-7479-4BBE-9335-5A1EDB1D8A21} (McAfee.com Operating System Class) - http://download.mcafee.com/molbin/sh...0/mcinsctl.cab
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://update.microsoft.com/windowsu...?1122039593358
O16 - DPF: {B38870E4-7ECB-40DA-8C6A-595F0A5519FF} (MsnMessengerSetupDownloadControl Class) - http://messenger.msn.com/download/ms...downloader.cab
O16 - DPF: {BCC0FF27-31D9-4614-A68E-C18E1ADA4389} (DwnldGroupMgr Class) - http://download.mcafee.com/molbin/sh...23/mcgdmgr.cab
O17 - HKLM\System\CCS\Services\Tcpip\..\{1B15BB9A-D1E7-473B-8EF6-B2B7889E0211}: NameServer = 194.72.0.98 194.72.9.34
O17 - HKLM\System\CS1\Services\Tcpip\..\{1B15BB9A-D1E7-473B-8EF6-B2B7889E0211}: NameServer = 194.72.0.98 194.72.9.34
O20 - Winlogon Notify: igfxcui - C:\WINDOWS\SYSTEM32\igfxsrvc.dll
O23 - Service: InCD Helper (InCDsrv) - Nero AG - C:\Program Files\Ahead\InCD\InCDsrv.exe
O23 - Service: McAfee.com McShield (McShield) - Unknown owner - c:\PROGRA~1\mcafee.com\vso\mcshield.exe
O23 - Service: McAfee SecurityCenter Update Manager (mcupdmgr.exe) - McAfee, Inc - C:\PROGRA~1\McAfee.com\Agent\mcupdmgr.exe
O23 - Service: McAfee.com VirusScan Online Realtime Engine (MCVSRte) - McAfee, Inc - c:\PROGRA~1\mcafee.com\vso\mcvsrte.exe
O23 - Service: McAfee Personal Firewall Service (MpfService) - McAfee Corporation - C:\PROGRA~1\McAfee.com\PERSON~1\MPFSERVICE.exe
O23 - Service: McAfee SpamKiller Server (MskService) - McAfee Inc. - C:\PROGRA~1\McAfee\SPAMKI~1\MSKSrvr.exe

Thanks